慢性荨麻疹患者生活质量评估及影响因素分析

Quality of Life and Analysis of Influencing Factors in Patients with Chronic Urticaria

目的探讨慢性荨麻疹(CU)对患者生活质量的影响。方法通过问卷调查形式收集CU患者的人口学资料、临床资料和皮肤病生活质量指数(DLQI),评估CU患者的生活质量及其影响因素。结果205例CU患者的DLQI评分为(7.59±5.58)分,对患者影响最显著的是症状(1.89±0.67)分,其次为感受(1.04±0.92)分和治疗(0.84±0.89)分。不同年龄组患者DLQI评分的差异有统计学意义(P<0.05);女性患者在感受和购物、家庭劳动方面的影响显著高于男性(均P<0.05)。患者DLQI评分与荨麻疹活动度评分(UAS)(r=0.560,P=0.000)和就诊次数(r=0.167,P=0.016)存在正相关,与初始发病年龄(r=-0.215,P=0.002)呈负相关。在患者感受方面,伴发血管性水肿患者的评分显著高于未伴发血管性水肿者(P<0.05)。结论CU对患者的生活质量有中等程度的影响。

Objective In order to explore the effects of chronic urticaria(CU)on the quality of life of patients.Methods The demographic data,clinical data and dermatology life quality index(DLQI)of patients with CU were collected by questionnaire to evaluate the quality of life and its influencing factors.Results The DLQI score of 205 patients with CU was 7.59±5.58.The most significant effect on the patients was symptoms(1.89±0.67),followed by feelings(1.04±0.92)and treatment(0.84±0.89).The differences of DLQI scores in different age groups have statistically significant(P<0.05);the influence of female patients on feeling,shopping and housework was significantly higher than that ofmale patients(P<0.05).The DLQI was positively correlated with urticaria activity score(UAS)(r=0.560,P=0.000)and number of visits(r=0.167,P=0.016),and negatively correlated with age of onset(r=-0.215,P=0.002).In terms of patients feelings,the score of patients with angioedema was significantly higher than that of patients without angioedema(P<0.05).Conclusion CU has a moderate impact on the quality of life of patients.