胰腺癌患者抑郁症发生危险因素的研究进展

Analysis of Risk Factors of Depression in Patients With Pancreatic Cancer

综合分析近10年国内外有关胰腺癌抑郁的相关文献,归纳总结胰腺癌伴发抑郁症状的临床流行病学、病因病机及危险因素的结果显示:胰腺癌相关抑郁的发病率位居肿瘤相关抑郁发病率的首位;胰腺癌患者出现抑郁症状多因脏腑虚衰,气滞、血瘀、痰凝等病理产物胶结日久而发,也与年龄、婚姻状态、遗传因素、肿瘤分期、治疗方式以及疼痛等影响因素明确相关,可能与性别、BMI、宗教信仰、不良生活习惯、疾病因素等因素相关,可在未来的研究中进一步明确。胰腺癌抑郁的发病率高,多种因素均能增加其患病风险。因此,应重视胰腺癌抑郁的预防,及时筛查识别高风险者,予以早期治疗。

A comprehensive analysis of the literature on pancreatic cancer depression in recent 10 years was made,the clinical epidemiology,etiology,pathogenesis and risk factors of pancreatic cancer with depressive symptoms were summarized.The incidence of pancreatic cancer-related depression was the first in the incidence of tumor-related depression.The main causes of depression in patients with pancreatic cancer are deficiency of the zang-fu viscera,so that qi stagnation,blood stasis,phlegm and other pathological products aggregation,it is also clearly related to age,marital status,genetic factors,tumor stage,treatment methods and pain,and may be related to factors such as gender,BMI,religious beliefs,bad living habits,disease factors,etc.,could be further clarified in future studies.The incidence of depression in pancreatic cancer is high,and multiple factors can increase the risk.Therefore,we should pay attention to the prevention of pancreatic cancer depression,timely screening and identification of high-risk individuals,early treatment.