摘要
The coronavirus disease 2019(COVID-19)is an emerging infectious disease caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Within a matter of months,this highly contagious novel virus has led to a global outbreak and is still spreading rapidly across continents.In patients with COVID-19,underlying chronic diseases and comorbidities are associated with dismal treatment outcomes.Owing to their immunosuppressive status,patients with hematological malignancies(HMs)are at an increased risk of infection and have a worse prognosis than patients without HMs.Accordingly,intensive attention should be paid to this cohort.In this review,we summarize and analyze specific clinical manifestations for patients with coexisting COVID-19 and HMs.Furthermore,we briefly de-scribe customized management strategies and interventions for this susceptible cohort.This review is intended to guide clinical practice.
新型冠状病毒肺炎(COVID-19)是一种由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的新型传染病.SARS-CoV-2具有极强的传染性,因此在引发流行病后又使其迅速升级为全球大流行,至今仍在部分国家迅速传播.在COVID-19的感染者中,存在肿瘤等慢性病或伴有相关合并症的患者预后往往较差.同时,由于恶性血液肿瘤患者长期处于免疫抑制状态,往往感染风险更高且预后更差,所以十分值得我们关注.这篇综述归纳并分析了恶性血液肿瘤患者合并COVID-19后的临床表现.此外,归纳了疫情期间恶性肿瘤的管理策略和感染后的综合干预措施,旨在为临床提供指导.
基金
Project supported by the National Natural Science Foundation of China(Nos.81770201 , 81730008)。
