肝泡型包虫病肺、脑转移的危险因素分析

Risk factors of lung and brain metastasiss of hepatic alveolar echinococcosis

目的探讨引起肝泡型包虫病肺、脑转移的危险因素。方法收集新疆医科大学第一附属医院2014年1月至2018年12月收治的225例肝泡型包虫病患者临床资料,根据是否发生肺、脑转移分为转移组(40例)和非转移组(185例),对两组患者的一般特征、病灶特征及检查结果进行分析。结果单因素分析发现两组性别、族别、来自疫区、病程、病灶长短径、包虫分型、血红蛋白水平差异有统计学意义(P<0.05)。Logistic回归结果显示性别为女性、来自疫区、长病程三个指标与肺、脑转移之间存在显著正相关关系(P<0.05),结论性别为女性、来自疫区、长病程是肝泡型包虫病患者肺、脑转移的独立危险因素。

Objective To explore the risk factors of lung and brain metastasis of hepatic alveolar echinococcosis.MethodsThe clinical data of 225 patients with hydatidosis admitted at the First Affiliated Hospital of Xinjiang Medical University from Jan 2014 to Dec 2018 was retrospectively analyzed.According to the occurrence of lung and brain metastasis,the patients were divided into metastasis group(40 cases)and non-metastatic group(185 cases).Results Univariate analysis showed that there were statistically significance in gender,ethnicity,epidemic area,course of disease,lesion diameter,hydatid type and hemoglobin level between two groups(P<0.05).logistic regression showed a significant metastasis tendency among female patients,those coming from epidemic area,and with long course of disease(P<0.05).Conclusion Female sex,those from epidemic area,and those with a long course of disease are independently risk factors of the lung and brain metastasis of hepatic alveolar echinococcosis.