温针灸联合清热活血汤治疗瘀毒内结证慢性盆腔炎临床研究

Clinical Study on Warming-Needle Moxibustion Combined with Qingre Huoxue Tang for Chronic Pelvic Inflammation with Stasis-Toxin Internal Accumulation Syndrome

目的:观察温针灸联合清热活血汤治疗瘀毒内结证慢性盆腔炎的临床疗效。方法:将120例患者随机分为试验组和对照组,每组60例。对照组给予清热活血汤治疗,试验组在对照组的基础上联合温针灸治疗。观察比较2组临床疗效以及治疗前后证候积分、血清白细胞介素-6(IL-6)及细胞黏附分子-1(ICAM-1)水平变化。结果:总有效率试验组为86.67%,对照组为66.67%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组中医证候积分均较治疗前明显下降(P<0.05),且试验组中医证候积分明显低于对照组(P<0.05)。治疗后,2组血清IL-6、ICAM-1水平均较治疗前明显降低(P<0.05),且试验组IL-6、ICAM-1水平均明显低于对照组(P<0.05)。结论:温针灸联合清热活血汤治疗女性慢性盆腔炎临床疗效显著,可有效改善患者临床症状及免疫功能,效果优于单纯中药治疗。

Objective:To observe the clinical effect of warming-needle moxibustion combined with Qingre Huoxue tang for chronic pelvic inflammation with stasis-toxin internal accumulation syndrome. Methods:A total of 120 cases of patients were randomly divided into the experiment group and the control group, 60 cases in each group. The control group was treated with Qingre Huoxue tang, and the experiment group was additionally treated with warming-needle moxibustion based on the treatment of the control group. The changes in syndrome scores as well asthe levels of interleukin-6(IL-6) and intercellular adhesion molecule-1(ICAM-1) in serum before and after treatment and clinical effect in the two groups were observed and compared. Results: The total effective rate was 86.67% in the experiment group and 66.67% in the control group, the difference being significant(P<0.05). After treatment, Chinese medicine syndrome scores in the two groups were significantlydecreased when compared with those before treatment(P<0.05),and the score in the experiment group was significantly lower than that in the control group(P<0.05). After treatment,the levels of IL-6 and ICAM-1 in serum in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the above levels in the experiment group were significantly lower than those in the control group(P<0.05). Conclusion:The therapy of warmingneedle moxibustion combined with Qingre Huoxue tang for chronic pelvic inflammation in women has significant clinical effect,and can effectively improve the clinical symptoms and immune function of the patients,whose effect is better than that of simple Chinese herbal medicine.