全身麻醉复合硬膜外麻醉对胃癌术后镇痛的影响研究

Effect of General Anesthesia Combined with Epidural Anesthesia on Postoperative Analgesia of Gastric Cancer

目的探究全身麻醉复合硬膜外麻醉对胃癌术后镇痛效果的影响。方法选取江南大学附属医院2017年9月至2020年5月收治的90例胃癌患者作为研究对象,采用随机数字表法分为对照组(45例)与观察组(45例)。对照组实施全身麻醉,观察组实施全身麻醉复合硬膜外麻醉。对比两组患者术后不同时段的视觉模拟疼痛(VAS)评分、24 h内术后镇痛(PCIA)按压次数及不良反应发生率。结果观察组患者术后不同时段的VAS疼痛评分均低于对照组,而术后24 h内PCIA按压次数低于对照组,且术后24 h的不良反应发生率显著低于对照组,组间比较差异均有统计学意义(P<0.05)。结论全身麻醉复合硬膜外麻醉可以减轻胃癌患者的术后疼痛,减少其PCIA按压次数,降低不良反应的发生率。

Objective To explore the effect of general anesthesia combined with epidural anesthesia on postoperative analgesia for gastric cancer.Methods From September 2017 to May 2020,90 patients with gastric cancer admitted to Affiliated Hospital of Jiangnan University were selected as the subjects.The patients were divided into control group and observation group with 45 cases in each group by random number table method.General anesthesia in the control group,the observation group was given general anesthesia combined with epidural anesthesia.The pain score,the number of PCIA compressions and the incidence VAS adverse reactions were compared between the two groups at different postoperative periods within 24 h.Results The VAS pain scores of the observation group at different time points after operation were lower than those of the control group,the PCIA pressing times in the observation group within 24 hours after operation were lower than those in the control group,the incidence of adverse reactions in the observation group was significantly lower than that in the control group,the differences between groups were statistically significant(P<0.05).Conclusion General anesthesia combined with epidural anesthesia can reduce postoperative pain in patients with gastric cancer,reduce the number of PCIA compressions,improve sedation,and reduce the incidence of adverse reactions.