肠道菌群与老年肌少症关系研究新进展

Research progress on relationship between intestinal flora and sarcopenia in the elderly

随着我国人口老龄化加剧,肌少症作为一种常见的老年综合征越来越受到关注。近年来研究认为肠道菌群的变化与骨骼肌功能的生理衰退有关,目前认为肠道菌群可直接通过炎性反应、激素水平以及营养、维生素的合成等方面对肌少症的发生发展产生影响。本文旨在对肌少症的发病机制以及肠道菌群变化所起的作用进行阐述。

Along with our country population aging,Sarcopenia,as a common Geriatric Syndrome,has attracted more and more attention.In recent years,studies have suggested that the changes of intestinal flora are related to the physiological decline of skeletal muscle function.Currently,it is believed that intestinal flora can directly affect the occurrence and development of sarcopenia through inflammatory response,hormone level,nutrition,vitamin synthesis and other aspects.This article aims to elucidate the pathogenesis of sarcopenia and the role of intestinal flora.