脓毒症与急性肾损伤

Sepsis and acute kidney injury

脓毒症是急性肾损伤(AKI)的主要病因,AKI是增加脓毒症病死率的独立危险因素。本文以一例经典病例:96岁老年男性脓毒症后AKI的诊治过程为例,结合脓毒症、AKI相关指南建议及解放军总医院老年肾科的诊治经验,详细阐述老年脓毒症、脓毒症休克后AKI的诊治建议,包括脓毒症的诊断标准、抗休克、抗感染、肾脏替代治疗、营养支持等综合治疗措施。为老年脓毒症后AKI的诊治提供帮助。

Sepsis is a major cause of acute kidney injury(AKI).AKI is an independent risk factor for increased sepsis mortality.A classic case of AKI after sepsis in a 96-year-old male was taken as an example to elaborate on the diagnosis and treatment recommendations for AKI after sepsis and septic shock.This recommendation is a combination of sepsis,AKI related guidelines and experience of geriatric nephrology in PLA general hospital.It includes the diagnostic criteria of sepsis,anti-shock,anti-infection,renal replacement therapy,nutritional support and other comprehensive treatmen.This review aims to provide help for the diagnosis and treatment of AKI after sepsis in the elderly.