急性缺血性卒中患者血栓成分和影像学表现的研究进展

Research progress of thrombus compositions and imaging manifestations in patients with acute ischemic stroke

近年来随着血管内介入治疗的快速发展,对急性缺血性卒中(AIS)患者血栓的研究日益加深,血栓的组成主要包括红细胞、纤维蛋白/血小板、白细胞、血管性血友病因子(vWF)及其他少见的成分,在非增强电子计算机断层扫描(NCCT)和磁共振成像(MRI)上可分别表现为动脉高密度征(HAS)及磁敏感血管征(SVS)。通过进一步分析其成分、影像学表现有助于了解AIS的病因、选择治疗方法、临床预后等。

With the rapid development of intravascular interventional treatment,the study of thrombus in patients with acute ischemic stroke(AIS)has been intensified in recent vears.The composition of thrombus mainly includes red blood cells,fibrin/platelets,white blood cells,and von Willebrand factor(vWF)and other rare components,which can be manifested as arterial hyperdensity sign(HAS)and susceptibility vessel sign(SVS)on non-contrast CT(NCCT)and magnetic resonance imaging(MRI).Further analysis of thrombus components and imaging manifestations will help to understand the etiology,treatment selection and clinical prognosis of AIS.