ACEF评分在急性ST段抬高型心肌梗死患者介入治疗后的预测价值

目的旨在探讨年龄、肌酐和射血分数(ACEF)评分是否能预测ST段抬高型心肌梗死患者经皮冠状动脉介入治疗(PCI)后的1年主要心脑血管事件(MACCE)发生情况。方法对2014年1月至2018年12月收治的接受PCI的ST段抬高型心肌梗死患者进行回顾性研究,分析1年内主要心脑血管事件(包括全因死亡、非致命性心肌梗死、非计划性血管重建和非致命性卒中)与临床相关因素以及ACEF评分的关系,并用曲线下面积来确定ACEF评分的精度。结果1年MACCE随ACEF评分的增加而增加(4.8%、11.8%和21.1%,P<0.001)。ACEF与MACCE的发生显著相关(OR:4.52,95%CI:2.89~6.95,P<0.001),且是MACCE发生的独立预测因素。经过AUC曲线分析,ACEF评分的预测精度与其他复杂评分系统相当(P>0.05)。结论简化的ACEF评分对经皮冠状动脉介入治疗的ST段抬高型心肌梗死患者的1年预后有较好的预测作用。

Objective To investigate whether the age,creatinine,and ejection fraction(ACEF)score can predict 1-year major cardiac and cerebrovascular events(MACCE)following ST-segment elevation myocardial infarction(STEMI)after percutaneous coronary intervention.Methods The data of the STEMI patients underwent PCI in our hospital from January 2014 to December 2018 were retrospectively analyzed.The relationship between 1-year major cardiovascular and cerebrovascular events(including all cause death,nonfatal myocardial infarction,unplanned revascularization,and nonfatal stroke),clinical related factors and ACEF score were analyzed.Accuracy of ACEF score was defined with area under the curve.Results The l-year MACCE increased in proportion increasing ACEF score(4.8%,11.8%and 21.1%,P<0.001).The ACEF score was significantly correlated with l-year MACCE(OR:4.52,95%CI:2.89~6.95,P<0.001),and was the independent predictor for 1-year MACCE.The prediction accuracy of ACEF score was similar to other complex scoring systems.Conclusion The simplified ACEF score can predict the 1-year outcomes of patients with STEMI after PCI.