2型糖尿病身体成分的特点及相关影响因素研究进展

Research progress on characteristics of body composition and its related influencing factors in patients with type 2 diabetes mellitus

2型糖尿病(type 2 diabetes mellitus,T2DM)已成为威胁人类健康的主要敌人之一,其管理成为一个重要的公共卫生问题。身体成分(包括脂肪、肌肉、骨密度)含量及分布的变化在T2DM的管理中受到广泛关注。越来越多的证据表明,T2DM与非糖尿病人群之间身体成分存在差异。除年龄、性别、种族等不可控因素外,代谢状况、降糖药物及生活方式等可控因素也影响着T2DM身体成分。目前,身体成分与T2DM之间的联系尚无定论。本研究回顾了T2DM身体成分的相关研究,综述T2DM身体成分含量及分布特点。同时回顾了代谢状况、降糖药物及生活方式对T2DM身体成分的影响,为T2DM的管理尤其是防治糖尿病相关并发症提供重要依据。

Type 2 diabetes mellitus(T2 DM)has become one of the main enemy threating human health,and its management has become an important public health problem.Content and distribution changes of body composition(including fat,muscle and bone mineral density)in the management of T2 DM have attracted extensive attention.A growing evidence demonstrates that there are differences in body composition between patients with and without T2 DM.In addition to uncontrollable factors such as age,gender and race,controllable factors such as metabolism,hypoglycemic drugs and lifestyle also influence the body composition of T2 DM.Currently,the association between body composition and T2 DM is still inconclusive.Based on this,this paper reviewed relevant studies on the body composition of T2 DM,summarized its content and distribution characteristics,and reviewed effects of metabolism,hypoglycemic drugs and lifestyle on it,providing an important basis for the management of T2 DM,especially the prevention and treatment of diabetes-related complications.