药物联合重复经颅磁刺激治疗对广泛性焦虑障碍患者认知功能的影响分析

The effect of drugs combined with repeated transcranial magnetic stimulation on the cognitive function of patients with generalized anxiety disorders

目的分析药物联合重复经颅磁刺激治疗对广泛性焦虑障碍患者认知功能的影响。方法79例广泛性焦虑障碍患者,根据治疗方法不同分为观察组(40例)与对照组(39例)。对照组行丁螺环酮治疗,观察组行丁螺环酮联合重复经颅磁刺激治疗。比较两组治疗前后心理状态、认知能力、治疗效果。结果治疗后,观察组汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分分别为(9.29±3.12)、(11.24±4.87)分,均低于对照组的(18.31±3.99)、(18.15±5.78)分,差异有统计学意义(P<0.05)。观察组的定向能力、注意力和延迟回忆评分均高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为97.50%,高于对照组的82.05%,差异有统计学意义(χ^2=5.178,P=0.023<0.05)。结论给予广泛性焦虑障碍患者丁螺环酮联合重复经颅磁刺激治疗能够有效改善患者的心理状态和认知能力,显著提升临床疗效,具有临床推广价值。

Objective To analyze the effect of drugs combined with repeated transcranial magnetic stimulation on the cognitive function of patients with generalized anxiety disorders.Methods A total of 79 patients with generalized anxiety disorder were divided into observation group(40 cases)and control group(39 cases)according to different treatment methods.The control group was treated with buspirone,and the observation group was treated with buspirone combined with repeated transcranial magnetic stimulation.The mental state,cognitive ability before and after treatment and treatment effect of the two groups were compared.Results After treatment,Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD)score of the observation group were(9.29±3.12)and(11.24±4.87)points,which were all lower than(18.31±3.99)and(18.15±5.78)points of the control group,and the difference was statistically significant(P<0.05).The orientation,attention and delayed recall score of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05).The total effective rate of treatment of the observation group was 97.50%,which was higher than 82.05%of the control group,and the difference was statistically significant(χ^2=5.178,P=0.023<0.05).Conclusion Buspirone combined with repeated transcranial magnetic stimulation can effectively improve the mental state and cognitive ability of patients with generalized anxiety disorder,and significantly improve the clinical efficacy,which is worthy of clinical promotion.