帕金森病患者脑深部电刺激术后的非运动症状及其对生活质量的影响

Non-motor symptoms after deep brain stimulation in patients with Parkinson's disease and its effect on quality of life

目的研究分析帕金森病患者脑深部电刺激术后的非运动症状及其对生活质量的影响。方法收集本院60例行脑深部电刺激术后的帕金森病患者临床资料,调查其非运动症状、生活质量。结果脑深部电刺激术后的帕金森病患者普遍存在非运动症状。Logistic多因素分析提示:病程、非运动症状量表总分、认知/情绪、心脑血管系统功能水平严重影响着帕金森病患者术后生活质量(P<0.05)。结论脑深部电刺激术治疗帕金森病患者之后,非运动症状表现明显,且对患者术后生活质量具有较大的影响,临床注重患者生活质量改善的同时也应当高度重视患者非运动症状的改善。

Objective:To study and analyze the non-motor symptoms after deep brain stimulation(DBS)in patients with Parkinson's disease and its effect on quality of life.Methods:Clinical data of 60 patients with Parkinson's disease after deep brain stimulation(DBS)in our hospital were collected to investigate their non-motor symptoms and quality of life.Results:After deep brain stimulation(DBS),Parkinson's disease patients generally had non-motor symptoms.Logistic multivariate analysis suggested that the course of disease,the total score of non-motor symptom scale,cognition/emotion,and the level of cardiovascular and cerebrovascular system function seriously affected the postoperative quality of life of pd patients(p<0.05).Conclusion:After deep brain stimulation(DBS)treatment for Parkinson's disease,non-motor symptoms are obvious and have a great impact on the postoperative quality of life of the patients.