升阳养血汤在干眼病患者中的应用

Efficacy of the Shengyang Yangxue decoction on xerophthalmia

目的:探讨升阳养血汤在干眼病患者中的应用。方法:选择2018年8月-2019年8月于本院治疗的78例干眼病患者,采用盲抽法分为观察组和对照组各39例。对照组采用玻璃酸钠滴眼液治疗,观察组在对照组基础上加用升阳养血汤治疗。比较两组临床疗效、临床症状积分、泪液分泌量、视觉功能相关生活质量量表评分(National Eye Institute Visual Function Questionnaire-25,NEI-VFQ-25)。结果:观察组临床总有效率较对照组高,差异有统计学意义(P<0.05)。治疗后,两组眼干涩、烧灼感、异物感与总积分均降低;且与对照组相比,观察组症状积分较低,差异有统计学意义(P<0.05)。治疗2周后,两组患者泪液分泌量均较治疗前多;且观察组多于对照组,差异有统计学意义(P<0.05)。治疗2周后,与对照组相比,观察组NEIVFQ-25评分高,差异有统计学意义(P<0.05)。结论:升阳养血汤治疗干眼病效果显著,可改善临床症状,促进泪液分泌,提高患者生活质量,值得临床推广应用。

Objective:To investigate efficacy of the Shengyang Yangxue decoction(升阳养血汤)on xerophthalmia.Methods:78 cases were divided into the observation group and the control group,39 cases in each.The control group was treated with sodium hyaluronate eye drops,and the observation group was treated with the Shengyang Yangxue decoction more.Results:The total clinical efficiency in the observation group was higher than the control group(P<0.05).After treatment,the dry eyes,burning sensation,foreign body sensation and total score in the two groups were all reduced.And those in the observation group were lower(P<0.05).After 2 weeks of treatment,the amount of tear secretion in both groups was higher than before treatment,and that in the observation group was better than the control group(P<0.05).The NEI-VFQ-25 score in the observation group was higher(P<0.05).Conclusion:The Shengyang Yangxue decoction on xerophthalmia shows good effects,can improve clinical symptoms,promote tear secretion,and improve the quality of life,and is worthy of clinical application.