厚朴排气合剂对急性脑卒中患者胃肠道功能的影响

Efficacy of the Houpo Paiqi mixture on gastrointestinal function in patients with acute cerebral apoplexy

目的:探讨厚朴排气合剂对急性脑卒中患者胃肠道功能的影响。方法:将60例急性脑卒中患者随机分为对照组和治疗组,每组各30例。对照组给予常规综合治疗,包括脱水、制酸护胃、营养神经、肠内营养支持等方案,治疗组在对照组基础上使用厚朴排气合剂50 mL,口服或者鼻饲,每天1次,连续2周。治疗2周后统计各组患者的中医证候积分、腹内压、肠道菌落数、急性生理和慢性健康状况Ⅱ(Acute Physiology and Chronic HealthⅡ,APACHEⅡ)评分,统计两组患者胃潴留发生率、吸入性肺炎发生率等指标。结果:治疗组治疗后双歧杆菌数、乳酸杆菌明显高于对照组,APACHEⅡ评分、腹内压明显低于对照组,胃潴留发生率、吸入性肺炎发生率明显低于对照组。结论:厚朴排气合剂能够改善急性脑卒中患者腹内压、调节肠道菌群,降低胃潴留、吸入性肺炎发生率,增强患者胃肠道功能,提高抢救成功率。急性生理和慢性健康状况评分。

Objective:To explore the efficacy of the Houpo Paiqi mixture(厚朴排气合剂)on gastrointestinal function in patients with acute cerebral apoplexy.Methods:60 cases were randomly divided into the control group and the treatment group,with 30 cases in each.The control group was given conventional comprehensive treatment,including dehydration,anti-acid and stomach protection,nourishing nerves,enteral nutrition support,etc..The treatment group was given the Houpo Paiqi mixture 50 mL more,oral or nasal feeding,once a day,for 2 weeks.Results:The number of bifidobacteria and lactobacilli in the treatment group after treatment were significantly higher than those in the control group.The APACHEⅡscore and intra-abdominal pressure were significantly lower than those in the control group.The incidence of gastric retention and aspiration pneumonia was significantly lower than the control group.Conclusion:The Houpo Paiqi mixture can improve the intra-abdominal pressure of patients,regulate the intestinal floras,reduce the incidence of gastric retention and aspiration pneumonia,enhance the gastrointestinal function of patients,and increase the success rate of rescue.