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m6A-RNA甲基化在非小细胞肺癌中的研究进展 被引量:3

Research progress of m6A-RNA methylation in non-small cell lung cancer
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摘要 N6-甲基腺嘌呤(N6-methyladenosine,m6A)是最常见的一种RNA表观遗传修饰。近年来,越来越多证据显示,m6A-RNA甲基化在非小细胞肺癌(non-small cell lung cancer,NSCLC)发生发展中起关键作用,其甲基化相关因子可作为促癌因子或抑癌因子调控NSCLC细胞增殖、迁移、侵袭、凋亡及细胞周期,可能是NSCLC治疗新靶点。本文就m6A-RNA甲基化在NSCLC中的研究进展作一综述。
作者 袁婷 莫碧文 YUAN Ting;MO Biwen
出处 《中国癌症防治杂志》 CAS 2020年第6期710-714,共5页 CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT
基金 国家自然科学基金项目(81760008)。
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