以颈部肿块为首发症状的套细胞淋巴瘤的临床分析

The clinical analysis of mantle cell lymphoma with cervical mass as the first symptom

目的探讨以颈部肿块为首发症状的套细胞淋巴瘤(MCL)的临床诊断、治疗及预后,提高对MCL的认识。方法结合文献对11例MCL患者的诊治过程进行回顾性分析。结果11例患者存活时间超过1年者10例,超过3年者7例,超过5年者2例。结论以颈部肿块为首发症状的MCL预后不良,是一种高度恶性的淋巴瘤,尽早行病理学检查,以利妥昔单抗联合CHOP的化疗方案能提高其3年生存期。

Objective To investigate the clinical diagnosis,treatment and prognosis of mantle cell lymphoma(MCL)with cervical mass as the first symptom,to improve the understanding of MCL.Method Combined with literature,the diagnosis and treatment process of 11 cases of MCL were retrospectively analyzed.Result Ten of the 11 patients survived for more than 1 year,seven for more than 3 years,and two for more than 5 years.Conclusion MCL with cervical mass as the first symptom has a poor prognosis and is a highly malignant lymphoma.Pathological examination should be completed as early as possible.Chemotherapy regimen of rituximab combined with chop can improve the 3-year survival period.