摘要
of main observation and conclusion A palladium catalyzed oxidative annulation of 1-hydroxy-o-carborane with internal alkynes via regioselective B(3)—H bond activation has been developed for facile synthesis of a series of QB-substituted carborane-fused oxaboroles.These molecules can undergo intramolecular oxidative dehydrogenative coupling to afford carborane-fused large n systems for potential applications in organic materials.The reaction mechanism is also proposed,involving hydroxy deprotonation,nucleopalladation of alkyne,regioselective electrophilic B—H substitution and reductive eiiimination.
基金
This work was supported by grants from the National NaturalScience Foundation of China(No.21772223)
the Science andTechnology Commission ofShanghai Municipality(No.18590760800)
the China Postdoctoral Science Foundation(No.BX20180341 to R.C.), the Shanghai Postdoctoral Excellence Program (No. 2018027 to R. C.), the Chinese Academy of Sciences,and Hong Kong Research Grants Council (No.14305017).