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影响慢性心力衰竭患者心脏再同步化治疗应答反应的因素分析

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摘要 目的:分析影响慢性心力衰竭患者心脏再同步化治疗(CRT)应答反应的因素。方法:回顾性分析2016年1月至2018年1月该院收治的120例慢性心力衰竭患者的临床资料。所有患者均给予CRT治疗,观察CRT应答情况,比较CRT应答和无应答患者的临床资料,分析影响慢性心力衰竭患者CRT应答反应的因素。结果:治疗后6个月,CRT应答率为76.67%(92/120)。CRT应答和无应答患者的性别、体质量指数、高血压占比、糖尿病占比、吸烟史占比、饮酒史占比、三酰甘油水平、低密度脂蛋白胆固醇水平、左心室舒张末期内径、左心房内径、右心室内径、QRS时限和心功能分级比较,差异均无统计学意义(P>0.05);CRT无应答患者年龄、病程、总胆固醇(TC)水平均明显高于CRT应答患者,左心室射血分数(LVEF)和高密度脂蛋白胆固醇(HDL-C)水平均明显低于CRT应答患者,差异有统计学意义(P<0.05);Logistic回归分析结果显示,年龄≥60岁、病程>3年、LVEF≤30%、TC≥6.0 mmol/L和HDL-C≤1.55 mmol/L均为慢性心力衰竭患者CRT无应答的危险因素(P<0.05)。结论:年龄≥60岁、病程>3年、LVEF≤30%、TC≥6.0 mmol/L和HDL-C≤1.55 mmol/L均为慢性心力衰竭患者CRT无应答的危险因素。
作者 宗晓娜
机构地区 登封市人民医院
出处 《中国民康医学》 2020年第23期109-111,共3页 Medical Journal of Chinese People’s Health
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