帕博丽珠单抗联合依托泊苷和铂类一线治疗小细胞肺癌:KEYNOTE-604研究

Pembrolizumab plus Etoposide and Platinum as First-Line Therapy for Small-Cell Lung Cancer:KEYNOTE-604 Study

1文献来源Rudin CM,Awad MM,Navarro A,et al.Pembrolizumab or placebo plus etoposide and platinum as first-line therapy for extensive-stage small-cell lung cancer:Randomized,double-blind,phaseⅢKEYNOTE-604 study[J].J Clin Oncol,2020,38(21):2369-2379.2证据水平1b。3背景依托泊苷联合铂类是广泛期小细胞肺癌(extensive-stage small-cell lung cancer,ES-SCLC)一线标准治疗方案之一。帕博丽珠单抗单药在小细胞肺癌中显示出抗肿瘤活性。