SPECT/CT与MRI及CT检查在前列腺癌骨转移诊断中的临床价值

Clinical value of SPECT/CT,MRI and CT in the diagnosis of bone metastasis of prostate cancer

目的探讨SPECT/CT与MRI及CT三种影像检查技术对前列腺癌(prostate cancer,PCa)骨转移的诊断效能。方法选取77例经病理确诊为前列腺癌的患者,进行SPECT/CT与MRI及CT三种影像学技术进行检查,并结合临床分析影像学表现。结果分析77例前列腺癌患者的各种影像学表现,结合临床最终确诊为骨转移者38例。77例均完成SPECT/CT全身骨扫描检查;同期完成盆腔CT检查者13例,完成盆腔MRI检查者69例。在同期完成CT检查的13例患者中,SPECT/CT诊断骨转移6例,CT诊断骨转移5例,最终临床确诊骨转移6例;在同期完成MRI检查的69例患者中,SPECT/CT诊断骨转移35例,MRI诊断骨转移34例,最终临床确诊骨转移35例。结论SPECT/CT影像检查技术灵敏度高,MRI影像检查特异度高,两种影像检查技术实现优势互补。

Objective The diagnostic efficacies of three imaging techniques of CT,MRI and SPECT/CT for bone metastasis of prostate cancer(PCa)are analyzed comparatively.Methods A total of 77 patients with pathologically diagnosed prostate cancer were collected and examined with SPECT/CT,MRI and CT imaging techniques,and the imaging findings were analyzed combined with clinical information.Results By analysis of various imaging findings of 77 patients with prostate cancer combined with clinical data,38 cases were diagnosed as bone metastases.All 77 patients received SPECT/CT whole-body bone scan;13 patients received the pelvic CT examination and 69 patients received pelvic MRI examination during the same period.Among 13 patients who received CT examination during the same period,SPECT/CT examination diagnosed bone metastasis in 6 patients,CT examination diagnosed bone metastases in 5 patients,and 6 cases were confirmed to have bone metastases finally.Among 69 patients received pelvic MRI examination during the same period,SPECT/CT examination diagnosed bone metastasis in 35 cases,MRI examination diagnosed bone metastases in 34 cases,and,finally,35 cases were confirmed to have bone metastases.Conclusion SPECT/CT imaging technology has high sensitivity,and MRI imaging has high specificity.The two imaging technologies have complementary advantages.