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CASPR2抗体相关的Isaacs综合征1例

Isaacs syndrome with CASPR2 antibody:A case report
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摘要 Isaacs综合征是一种因周围神经过度兴奋引起的疾病,其特征是广泛的肌肉颤搐和僵硬。最近的研究显示CASPR2抗体可能是Isaacs综合征的致病性抗体之一。现将笔者2019年在昆明医科大学第一附属医院遇到的1例CASPR2抗体阳性的以肌肉疼痛为主要表现的Isaacs综合征报告如下。 Isaacs syndrome is a disease of peripheral nerve hyperexcitability,characterized by widespread muscle twitching and stiffness.More recent evidence suggests that CASPR2 antibody may be one of the pathogenic autoantibodies in Isaacs syndrome.We report a case of Isaacs syndrome with muscle pain as the main clinical manifestation and positive CASPR2 antibody from First Affiliated Hospital of Kunming Medical University in 2019.
作者 张凌峰 刘彬 ZHANG Lingfeng;LIU Bin(Department of Geriatric Neurology,First Affiliated Hospital of Kunming Medical University,Kunming 650000,China)
出处 《临床与病理杂志》 2020年第12期3317-3319,共3页 Journal of Clinical and Pathological Research
关键词 ISAACS综合征 CASPR2抗体 肌肉疼痛 Isaacs syndrome CASPR2 antibody muscle pain
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