摘要
Malignant melanoma(MM)is a kind of highly-invasive and highly-metastatic tumor,which is insensitive to radiochemotherapy.It is also one of the most invasive tumors in skin cancer with limited treatment options.Due to its rapid increase in incidence in recent years and the limitations of monotherapy,it is necessary to use combination therapy.The combination therapy can not only enhance the treatment effect,but also avoid the development of drug resistance as much as possible.This paper focused on the combined therapy of targeted traditional therapies,immunotherapy with radiotherapy and chemotherapy or other traditional therapies,as well as the research status and new developments of these combined therapies.
基金
Public Welfare Technology Application Research Program of Zhejiang Province(LGF18H160034,LGD20H300001,2015C37125)
2019 National Undergraduate Innovation Training Program(20190354034)
2018 Zhejiang Science and Technology Innovation Activity Program(Emerging talent Program)(2018R417029)
2018 Jiaxing Key Technology Innovation Team
2018 SRT Key Project of Jiaxing University(85178428)。
