利拉鲁肽对肥胖2型糖尿病患者尿蛋白治疗的疗效分析

Analysis of the Effect of Liraglutide on Urine Protein in Obese Patients with Type 2 Diabetes Mellitus

目的利拉鲁肽对肥胖2型糖尿病患者尿蛋白的疗效分析。方法选取2018年1月至2019年1月在大连市友谊医院内分泌科就诊的80例肥胖2型糖尿病患者,随机分组,对照组(40例)采取常规治疗,试验组(40例)在对照组的基础上采取利拉鲁肽治疗,比较两组患者的临床有效率和尿微量白蛋白和血糖控制情况。结果试验组临床有效率为87.50%,对照组临床有效率为75%,试验组高于对照组,差异有统计学意义(P<0.05);通过试验数据分析,试验组的尿A/C、FPG、2 hPG、HbA1c数据优于对照组,差异有统计学意义(P<0.05)。结论肥胖2型糖尿病患者采取利拉鲁肽治疗,可以有效的提高临床有效率,降低患者的尿微量白蛋白含量,控制血糖水平。

Objective To analyze the effi cacy of liraglutide in the treatment of obese type 2 diabetes mellitus.Methods From January 2018 to January 2019 in endocrinology of Dalian Friendship Hospital,80 cases of obese patients with type 2 diabetes,were randomly divided into experimental group and control group,the control group(40 cases)treated with conventional treatment,experimental group(40 cases)was treated with liraglutide on the basis of the control group,compared two groups of patients with the clinical effi cient and the urine trace albumin and blood sugar control.Results The clinical effective rate of the experimental group was 87.50%,and that of the control group was 75%.The experimental group was higher than the control group,and the diff erence was statistically signifi cant(P<0.05).Through data analysis,urine A/C,FPG,2 hPG and HbA1c data of the experimental group were better than that of the control group,and the diff erence was statistically signifi cant(P<0.05).Conclusion Liraglutide treatment for obese type 2 diabetes mellitus can eff ectively improve the clinical effi ciency,reduce the content of urinary microalbumin in patients,and control the level of blood glucose.