复方聚乙二醇电解质散联合二甲硅油散对老年患者结肠镜检查前肠道准备效果的影响

Effect of polyethylene glycol electrolytes powder combined with dimethicone powder on intestinal preparation before colonoscopy in elderly patients

目的观察复方聚乙二醇电解质散联合二甲硅油散对老年患者结肠镜检查前肠道准备效果的影响。方法选择2015年8月至2018年8月于上海交通大学附属第六人民医院接受电子结肠镜检查的126例老年患者,使用随机数字表法将其分为观察组和对照组,每组各63例。于检查前给予所有患者复方聚乙二醇电解质散,观察组患者加用二甲硅油散水溶液口服。比较两组患者肠道准备不良反应、肠道清洁度、肠道内气泡量评分、肠镜检查时间、生理盐水冲洗量、病灶检出率。结果观察组患者肠道准备不良反应总发生率显著低于对照组(P<0.05),肠道内气泡量总评分和病灶检出率均显著高于对照组(均P<0.05),肠镜检查时间显著短于对照组(P<0.05),生理盐水冲洗量显著少于对照组(P<0.05)。两组患者肠道清洁度总评分比较差异无统计学意义(P>0.05)。结论复方聚乙二醇电解质散联合二甲硅油散能够降低老年患者结肠镜检查前肠道准备不良反应发生率,减少肠道内气泡量,对于改善检查视野、提高病灶检出率均具有积极作用。

Objective To observe the effect of polyethylene glycol electrolytes powder combined with dimethicone powder on intestinal preparation before colonoscopy in elderly patients.Method A total of 126 elderly patients scheduled to undergo electronic colonoscopy in Shanghai Jiaotong University Affiliated Sixth People's Hospital divided into observation group and control group by random number table method,with 63 patients in each group,they were given polyethylene glycol electrolytes powder before examination,while observation group patients were given dimethicone powder.The adverse reactions of intestinal preparation,intestinal cleanliness,intestinal bubble volume score,enteroscopy time,saline irrigation volume and lesion detection rate were compared between the two groups.Result The total incidence of adverse reactions due to intestinal preparation in observation group was significantly lower than that in control group(P<0.05),the total score of intestinal bubble volume and lesion detection rate were significantly higher than those in control group(all P<0.05),the duration of enteroscopy was significantly shorter than that in control group(P<0.05),the amount of normal saline washing was significantly less than that in control group(P<0.05).There was no significant difference in the total scores of intestinal cleanliness between the two groups(P>0.05).Conclusion Polyethylene glycol electrolytes powder combined with dimethicone powder can reduce the incidence of adverse reactions of intestinal preparation before colonoscopy in elderly patients,reduce the amount of intestinal bubbles,improve the visual field of examination and the detection rate of lesions.