前列舒乐颗粒联合盐酸坦洛新缓释胶囊治疗良性前列腺增生合并慢性前列腺炎的疗效观察

Efficacy of Qianlie Shule Granules combined with Tamsulosin Hydrochloride Sustained-Release Capsules for treating benign prostatic hyperplasia complicated with chronic prostatitis

目的观察前列舒乐颗粒联合盐酸坦洛新缓释胶囊治疗良性前列腺增生(BPH)合并慢性前列腺炎(CP)患者的疗效。方法将64例BPH合并CP患者采用随机数字表法分为观察组和对照组,每组32例。对照组患者给予口服盐酸坦洛新缓释胶囊治疗,观察组在此基础上加用前列舒乐颗粒治疗,两组均治疗3个月。比较两组疗效,以及治疗前后国际前列腺症状评分(IPSS)、生活质量量表(QOL)评分、最大尿流率。结果观察组患者治疗总有效率高于对照组,临床疗效优于对照组(均P<0.05)。治疗后,两组患者IPSS评分均低于治疗前,QOL评分及最大尿流率均高于治疗前,且观察组IPSS评分低于对照组,QOL评分及最大尿流率均高于对照组(均P<0.05)。结论前列舒乐颗粒联合盐酸坦洛新缓释胶囊治疗BPH合并CP患者疗效确切,可明显改善患者前列腺症状及生活质量,提高患者排尿效果。

Objective To observe the efficacy of Qianlie Shule Granules combined with Tamsulosin Hydrochloride Sustained-Release Capsules for the treatment of patients with benign prostatic hyperplasia(BPH)combined with chronic prostatitis(CP).Methods Sixty-four BPH patients with concomitant CP were divided into observation group and control group using the random number table method,with 32 cases in each group.Patients in the control group were given oral Tamsulosin Hydrochloride Sustained-Release Capsules,based on which the observation group received additional Qianlie Shule Granules.Both groups were treated for three months.The efficacy as well as the International Prostate Symptom Score(IPSS),Quality of Life Scale(QOL)score,and maximum urine flow rate(Q max)before and after treatment was compared between the two groups.Results The observation group had higher total effective rate for treatment and superior clinical efficacy than the control group(all P<0.05).After treatment,IPSS scores were decreased and QOL scores and Q max were increased in both groups as compared with those before treatment,moreover,the observation group exhibited lower IPSS scores and higher QOL scores and Q max than the control group(all P<0.05).Conclusion For patients with BPH complicated with CP,Qianlie Shule Granules combined with Tamsulosin Hydrochloride Sustained-Release Capsules provides a definite efficacy,which can significantly ameliorate prostate symptoms and quality of life and improve urination effect in the patients.