增强3D-FLAIR特征对突发性感音神经性听力损失患者预后的预测价值

Prognostic Value of Enhanced 3D-FLAIR Characteristics in Patients with Sudden Sensorineural Hearing Loss

本文探讨了增强内耳磁共振三维快速液体衰减反转恢复序列(3D-FLAIR)特征对突发性感音神经性听力损失(SNHL)患者预后的预测价值。以89例单耳SNHL患者为研究对象,所有患者均行3D-FLAIR检查并统计相关资料,且在完整周期治疗后均进行为期6个月的随访。结果显示,在完成随访的87例患者中,预后良好64例,预后不良23例。预后良好患者的纯音测听阈平均值(PTA)、水成像扫描膜迷路结构异常占比均显著低于预后不良患者,而两组患者3D-FLAIR扫描结果也存在显著差异(P<0.05)。PTA、3D-FLAIR扫描信号是影响SNHL患者预后的独立因素。PTA、3D-FLAIR及二者联合对患者预后均有较好的预测价值(P<0.05)。联合检测的AUC显著大于PTA和3D-FLAIR,约登指数高于PTA和3D-FLAIR。表明3D-FLAIR对于SNHL患者预后具有一定的预测效能,但仍需联合其他有效的检测方式进一步提升判断SNHL患者预后的效果。

This article discusses the predictive value of enhanced inner ear magnetic resonance 3D-FLAIR characteristics for the prognosis of sudden sensorineural hearing loss(SNHL)patients.This study took 89 single-ear SNHL patients as the research object.All patients underwent 3D-FLAIR examination and related data,and they were followed up for 6 months after a complete cycle of treatment.The results showed that of the 87 patients who completed the follow-up,64 had a good prognosis and 23 had a poor prognosis.The average pure tone audiometry threshold(PTA)and the proportion of abnormal membrane labyrinth structure in water imaging scan of patients with good prognosis were significantly lower than those of patients with poor prognosis,and there were also significant differences in 3D-FLAIR scan results between the two groups(P<0.05).PTA and 3D-FLAIR scanning signals are independent factors affecting the prognosis of SNHL patients.PTA,3D-FLAIR and the combination of the two have good predictive value for the prognosis of patients(P<0.05).The combined detection of AUC was significantly greater than PTA and 3D-FLAIR,and the Youden index was higher than PTA and 3D-FLAIR.It shows that 3D-FLAIR has a certain predictive power for the prognosis of SNHL patients,but it still needs to be combined with other effective detection methods to further improve the effect of judging the prognosis of SNHL patients.