饮酒与牙周炎的相关性研究进展

Research progress on the relationship between alcohol consumption and periodontitis

乙醇代谢与氧化应激有关,导致与细胞死亡或细胞周期停滞等炎症过程相关的细胞改变。酒精摄入会导致骨质破坏,并改变白细胞介素、金属蛋白酶和促炎信号的表达。然而,现有研究关于酒精摄入对牙周炎的潜在作用的报道缺乏一致性,对其作用机制更是知之甚少。该综述通过归纳酒精摄入对牙周炎的影响,提出其可能的作用机制,为后续的研究方向提供思路。

Ethanol metabolism is related to oxidative stress,leading to cell changes inflammatory processes such as cell death or cell cycle arrest.Alcohol intake can lead to bone destruction and change the expression of interleukin,metalloproteinase and pro-inflammatory signal.However,reports about the potential effect of alcohol intake on periodontitis lack consistency,and the mechanism of its effect is even less known.This review summarized the effect of alcohol intake on periodontitis,proposed its possible mechanism and provided ideas for follow-up research.