营养监测对老年食管癌术后病人生活质量的影响

Effect of nutrition monitoring on quality of life in elderly patients with esophageal cancer after operation

目的探讨营养监测对老年食管癌术后病人营养状态及生活质量的影响。方法选择2016年1月至2019年5月辽宁省肿瘤医院胸外科收治的96例老年食管癌病人,按照随机数字表将病人分为2组对照组(48例)术后给予常规肠内营养支持;观察组(48例)术后给予营养监测指导下营养支持治疗。2组均干预至出院。比较2组干预前后营养指标[血清白蛋白(ALB)、血清前白蛋白(PA)、Hb、转铁蛋白(TRF)、上臂三头肌肌围(AMC)]和生活质量评分的变化。结果观察组的术后住院时间明显短于对照组,并发症发生率明显低于对照组,差异均有统计学意义(P<0.05)。干预后,观察组ALB、PA、Hb、TRF、AMC水平均显著高于对照组和干预前(P<0.05),对照组ALB、PA、Hb、TRF、AMC水平较干预前无明显变化(P>0.05);2组健康状况调查简表(SF-36)各维度评分均高于干预前,且观察组SF-36各维度评分均显著高于对照组,差异有统计学意义(均P<0.05)。结论营养监测指导下的营养支持干预可更好地改善老年食管癌病人术后营养状态,提高其生活质量。

Objective To investigate the effect of nutrition monitoring on the nutritional status and quality of life in the elderly patients with esophageal cancer after operation.Methods A total of 96 elderly patients with esophageal cancer from January 2016 to May 2019 were randomly divided into two groups the control group(48 cases)receiving routine enteral nutrition support after operation,and the observation group(48 cases)receiving nutrition support under the guidance of nutrition monitoring after operation.Both groups were intervened until discharge.The levels of nutritional indexes such as albumin(ALB),prealbumin(PA),hemoglobin(Hb),transferrin(TRF),arm muscle circumference(AMC)and the MOS item short from health survey(SF-36)scores before and after intervention were compared.Results After intervention,the time of hospitalization was significantly shorter and the incidence rate of complications was significantly lower in the observation group than that in the control group(P<0.05);The levels of ALB,PA,Hb,TRF and AMC in the observation group were higher than those in the control group and those before intervention(P<0.05),but there were no significant differences in the above indicators in the control group before and after intervention;The scores of SF-36 in both groups were higher than those before intervention(P<0.05),especially in the observation group(P<0.05).Conclusions Nutritional support intervention under the guidance of nutrition monitoring can improve the nutritional status and quality of life in the elderly patients with esophageal cancer after operation.