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左室射血分数与QRS波时程比值评价射血分数保留的老年心力衰竭病人心功能的价值 被引量:5

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摘要 CHF是多种心脏疾病的终末阶段,也是心因性死亡的主要原因[1-2]。研究显示,约50%的心衰病人仍然保留相对正常的LVEF,即射血分数保留的心力衰竭(heart failure with preserved ejection fraction,HFpEF),且预后可能更差[3-4]。然而临床认为仅凭LVEF评估HFpEF病人心功能的价值有限,因其无法反映心脏收缩的敏捷性、时效性及心脏每搏输出量[5-6]。QRS波可反映心室除极过程的综合时间,有研究证实,QRS波时程(QRS duration,QRSd)与心室功能结构损害密切相关[7-8],然其本身并非心功能评估指标[9]。因此,本研究结合LVEF和QRSd的特征,探究两者比值(TEF)评价老年HFpEF病人心功能的可行性,现报道如下。
出处 《实用老年医学》 CAS 2021年第1期71-73,共3页 Practical Geriatrics
基金 江苏大学医学临床科技发展基金项目(JLY20160030)。
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  • 1托伐普坦临床研究协作组,张健,朱文玲.常规治疗基础上联用托伐普坦片治疗心原性水肿的有效性和安全性的多中心随机、双盲、安慰剂对照研究[J].中华心力衰竭和心肌病杂志(中英文),2017,1(1):15-21. 被引量:26
  • 2庞晓,刘红阳,王月香,席燕.充血性心力衰竭患者血浆一氧化氮、内皮素-1与肿瘤坏死因子-α的含量及其临床意义[J].临床心血管病杂志,2006,22(5):310-311. 被引量:4
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