呼吸衰竭患者120例应用高流量湿化吸氧与双气道正压通气的临床疗效分析

Clinical effect analysis of HFNC and BiPAP in 120 patients with respiratory failure

目的:研究高流量湿化吸氧(HFNC)与双水平气道正压通气(BIPAP)治疗呼吸衰竭的应用效果。方法:2018年2月-2019年10月收治呼吸衰竭患者120例,随机分为两组,各60例。A组给予HFNC治疗;B组给予BIPAP治疗。比较两组治疗效果。结果:两组治疗后Apache-Ⅱ评分、OI水平均优于治疗前,差异有统计学意义(P<0.05);B组治疗后PaCO2水平较治疗前明显降低,差异有统计学意义(P<0.05)。两组治疗后Apache-Ⅱ评分比较,差异无统计学意义(P>0.05);A组治疗后OI水平升高程度优于B组,差异有统计学意义(P<0.05);B组治疗后PaCO2水平下降程度优于A组,差异有统计学意义(P<0.05)。A组患者舒适度及耐受性评分均明显优于B组,差异有统计学意义(P<0.05)。结论:两种方式均可以用于治疗呼吸衰竭患者,但HFNC更适用于Ⅰ型呼吸衰竭患者,而BIPAP更适用于Ⅱ型呼吸衰竭患者。HFNC的舒适度及耐受性好,更适用于精神紧张、焦虑及患有幽闭恐惧症等依从性差的患者。

Objective:To study the application effect of high flow humidification oxygen inhalation(HFNC)and biphasic positive airway pressure(BiPAP)in the treatment of respiratory failure.Methods:From February 2018 to October 2019,120 patients with respiratory failure were selected and randomly divided into two groups with 60 patients in each group.Group A was treated with HFNC and group B was treated with BiPAP.We compared the therapeutic effects of the two groups.Results:Apache-Ⅱscore and OI level of the two groups after treatment were better than those before treatment,the difference was statistically significant(P<0.05).In group B,after treatment,PaCO2 level was significantly lower than that before treatment,the difference was statistically significant(P<0.05).There was no significant difference in Apache-Ⅱscore between the two groups after treatment(P>0.05).In group A,after treatment,the increase of OI level was better than that in group B,the difference was statistically significant(P<0.05).In group B,after treatment,the decrease of PaCO2 level was better than that in group A,the difference was statistically significant(P<0.05).The scores of comfort and tolerance in group A were significantly better than those in group B,the difference was statistically significant(P<0.05).Conclusion:Both methods can be used to treat patients with respiratory failure,but HFNC is more suitable for patients with type I respiratory failure,and BiPAP is more suitable for patients with type II respiratory failure.HFNC has good comfort and tolerance,and is more suitable for patients with mental stress,anxiety and claustrophobia.