摘要
在环状偶氮次甲基亚胺类1,3-偶极子中,C,N-环状偶氮次甲基亚胺是使用最广泛的反应试剂,用于结构多样化的四氢异喹啉衍生物的构建.简单综述了C,N-环状偶氮次甲基亚胺参与的反应研究进展,重点介绍[3+2]、[3+3]、[3+4]、[5+1]、[3+1]环加成以及其他反应,并讨论了反应的特点、反应过程及合成应用,最后展望了它的发展前景.
Among various 1,3-dipoles of cyclic azomethine imines, C,N-cyclic azomethine imines are the most widely used reagents in the construction of diverse tetrahydroisoquinoline derivatives. The developments of reactions with C,N-cyclic azomethine imines including [3+2], [3+3], [3+4], [5+1], [3+1] cycloaddition reactions and miscellaneous reactions are summarized. The properties of reactions, reaction processes and synthetic applications are discussed. Finally, the prospects of the reaction with this reagent are also proposed.
作者
华庭碧
阳青青
肖文精
Hua Tingbi;Yang Qingqing;Xiao Wengjing(Hubei Key Laboratory of Natural Products Research and Development,China Three Gorges University,Tichang,Hubei 443002;Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials,College of Materials and Chemical Engineering,China Three Gorges University,Yichang,hubei 443002;Key Laboratory of Pesticide&Chemical Biology,Ministry of Education,College of Chemistry,Central China Normal University,Wuhan 430079)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2020年第11期3559-3595,M0005,共38页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21702121)
三峡大学天然产物研究与利用湖北重点实验室开放基金(No.NPRD-2018010)、三峡大学学位论文培优基金和高等学校学科创新引智计划(111计划,No.D20015)资助项目
