腹腔镜手术应用于子宫内膜癌治疗中的效果观察及安全性评价

Effect observation and safety evaluation of laparoscopic surgery in the treatment of endometrial cancer

目的探究腹腔镜手术应用于子宫内膜癌治疗中的效果及安全性。方法本研究中的观察对象均为本院接收的210例子宫内膜癌患者,上述患者入院时间均在2015年1月~2019年6月。分析上述患者的病历资料,依据治疗方案分为对照组和观察组,其中对照组105例患者接受传统开腹手术治疗,观察组105例患者给予腹腔镜手术治疗。比较两组患者手术指标、手术效果、复发率、无瘤生存率及并发症发生情况。结果观察组手术耗时[(208.81±8.36)min]长于对照组,术中出血量[(204.15±20.72)mL]、术后肛门排气时间[(36.41±3.32)d]、导尿管留置时间[(2.03±0.46)d]及住院时间[(9.58±2.76)d]均明显少于对照组(P<0.05);观察组盆腔淋巴结切除数目[(24.71±1.19)枚]和腹主动脉旁淋巴结切除数目[(4.09±0.96)枚]同对照组[(24.95±1.26)枚、(4.24±1.08)枚]比较,差异无统计学意义(P>0.05);观察组并发症总发生率(1.90%)明显低于对照组(P<0.05);两组复发率(1.90%vs 0.00%)、无瘤生存率(96.19%vs 99.05%)比较,差异无统计学意义(P>0.05)。结论腹腔镜手术应用于子宫内膜癌治疗中的效果显著,且术后并发症发生风险较低。

Objective To explore the effect and safety of laparoscopic surgery in the treatment of endometrial cancer.Methods The subjects of observation in this study were collected from all 210 patients with endometrial cancer who were admitted to our hospital.The admission time of the above patients was from January 2015 to June 2019.The medical data of the above patients were analyzed.According to the treatment plan,they were divided into a control group and an observation group.Among them,105 patients in the control group were given traditional open surgery.105 patients in the observation group were given laparoscopic surgery.The surgical indicators,surgical effects,recurrence rate,tumor-free survival rate and complications were compared between the two groups of patients.Results The operation time([208.81±8.36]min)in the observation group was longer than that in the control group.Intraoperative blood loss([204.15±20.72]mL),postoperative anal exhaust time([36.41±3.32]d),catheter indwelling time([2.03±0.46]d)and length of hospitalization time([9.58±2.76]d)were significantly less than those in the control group(P<0.05);the number of removed pelvic lymph nodes(24.71±1.19)and the number of removed para-abdominal aortic lymph nodes(4.09±0.96)in the observation group were compared with those in the control group(24.95±1.26,4.24±1.08)(P>0.05);the complication total rate(1.90%)in the observation group was significantly lower than that in the control group(P<0.05);there was no significant difference in recurrence rate(1.90%vs 0.00%)and tumor free survival rate(96.19%vs 99.05%)between the two groups(P>0.05).Conclusion Laparoscopic surgery is effective in the treatment of endometrial cancer and the risk of postoperative complications is low.