淋巴结清扫术在肝内胆管细胞癌中的应用

Application of lymph node dissection in intrahepatic cholangiocarcinoma

肝内胆管细胞癌(intrahepatic cholangiocarcinoma,ICC)在肝脏原发恶性肿瘤发病率中位列第二。其恶性度高,手术切除是唯一有效的根治性治疗手段。同时,该肿瘤术后复发风险高、预后差,其影响预后的因素多样。淋巴结转移是影响预后的重要危险因素之一。作为明确N分期为主要目的之一,淋巴结清扫术被各项指南作为手术常规流程并进行推荐。但是,淋巴结清扫术对预后的价值尚不明确,其适应证、清扫范围等问题也存在争议。因此,本文结合文献就此方面进行全面的综述。

Intrahepatic cholangiocarcinoma is the second common primary malignant tumors of the liver with high degree of malignancy,and surgery is the only effective radical treatment.This tumor has a poor prognosis and a high risk of postoperative recurrence,and its risk factors are diverse.Lymph node metastasis is one of the most important risk factors.As one of the main purposes of defining N staging,regional lymph node dissection is also recommended in all guidelines as a routine surgical procedure.However,the prognostic value of lymph node dissection is still unclear,and its indications and scope of dissection are still controversial.Therefore,this article combines the literature to carry on the comprehensive review in this aspect.