摘要
在抗结核化疗中导致患者中止抗结核治疗,影响治疗效果最常见的药物不良反应即是抗结核药物性肝损伤(anti⁃tuberculosisdrug⁃inducedliverinjury,ATB⁃DILI)。ATB⁃DILI的正确预防、诊断、处置在结核治疗过程中尤为重要,本文将重点论述ATB⁃DILI的发生机制、临床诊治和抗结核治疗预防保肝的必要性,以期为ATB⁃DILI的规范处置提供参考。
Anti⁃tuberculosis drug⁃induced liver injury(ATB⁃DILI)was the most common adverse drug reaction in anti⁃tuberculosis treatment,which was one of the reasons that caused patients to stop anti⁃tuberculosis treatment.It then affectes the therapeutic effect of tuberculosis.This article focuses on the pathogenesis,clinical diagnosis and treatment of ATB⁃DILI,and the necessity of prevention and liver protection in anti⁃tuberculosis treatment,which provided a reference for the standardized diagnosis and treatment of ATB⁃DILI.
作者
钟洪兰
ZHONG Honglan(Department of Pharmacy,Guangzhou Chest Hospital,Ganzhou 510095,China)
出处
《实用医学杂志》
CAS
北大核心
2020年第24期3307-3311,共5页
The Journal of Practical Medicine
关键词
抗结核药物性肝损伤
发生机制
临床诊治
预防保肝
anti⁃tuberculosis drug⁃induced liver injury
occurrence mechanism
clinical diagnosis and treatment
prevention and liver protection
