生长抑素联合大承气汤加减治疗急性胰腺炎的效果

Effect of somatostatin combined with modified Dachengqi decoction in the treatment of acute pancreatitis

目的探讨生长抑素联合大承气汤加减治疗急性胰腺炎(AP)的效果。方法选取2017年5月至2019年1月本院的60例AP患者,依据随机数字表将其分为A组和B组,每组30例。A组给予生长抑素+常规治疗,B组在A组基础上给予大承气汤加减治疗。比较两组的治疗效果。结果治疗后,两组的血、尿AMS水平均低于治疗前,且B组低于A组(P<0.05)。B组的腹痛、腹胀、恶心呕吐缓解时间及血、尿AMS水平恢复正常时间均短于A组(P<0.05)。B组的治疗总有效率高于A组(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论生长抑素联合大承气汤加减治疗可有效改善AP患者临床症状,有利于提高治疗效果,且安全性好,值得临床推广。

Objective To investigate the effect of somatostatin combined with modified Dachengqi decoction in the treatment of acute pancreatitis(AP).Methods A total of 60 cases of AP patients in our hospital from May 2017 to January 2019 were selected and divided into group A and group B according to the random number table,with 30 cases in each group.The group A was given somatostatin+conventional treatment,and the group B was given modified Dachengqi decoction treatment on the basis of the group A.The therapeutic effects of the two groups were compared.Results After treatment,the blood and urine AMS levels of the two groups were lower than those before treatment,and those in the group B were lower than the group A(P<0.05).The remission time of abdominal pain,abdominal distension,nausea and vomiting,and the recovery time of blood and urine AMS levels in the group B were shorter than those in the group A(P<0.05).The total effective rate of treatment in the group B was higher than that in the group A(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Somatostatin combined with modified Dachengqi decoction can effectively improve the clinical symptoms of AP patients,it is helpful to improve the therapeutic effect,and has good safety,which is worthy of clinical promotion.