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阿托伐他汀联合曲美他嗪对冠心病心绞痛患者心室重构及心血管事件的影响 被引量:4

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摘要 目的观察阿托伐他汀联合曲美他嗪对冠心病不稳定型心绞痛患者心室重构及不良心血管事件的影响。方法选择2019年1月至2020年2月于河南科技大学第一附属医院治疗的110例冠心病不稳定型心绞痛患者进行研究,按随机数字表法分组,对照组55例患者接受经皮冠状动脉介入治疗(PCI),并服用阿托伐他汀钙片,研究组55例患者在对照组基础上服用盐酸曲美他嗪片,两组均连续治疗6个月,治疗前、后检测两组患者左室收缩末期内径(LVESD)、左心室射血分数(LVEF)、左室舒张末期内径(LVEDD)、左室质量指数(LVMI)水平,治疗后统计两组不良心血管事件发生率。结果治疗后研究组LVEF水平高于对照组,LVESD、LVEDD、LVMI水平低于对照组(P<0.05)。研究组不良心血管事件发生率(5.45%)低于对照组(14.55%),差异无统计学意义(P>0.05);研究组总有效率高于对照组(P<0.05)。结论阿托伐他汀联合曲美他嗪可改善冠心病不稳定型心绞痛患者心室重构情况,提升疗效。
出处 《河南医学研究》 CAS 2020年第36期6813-6815,共3页 Henan Medical Research
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