浅析第一批经典名方中的炮制特点及考证方法建议

Brief study on processing characteristics of first batch of classical prescriptions and suggestions on textual research

经典名方是中药新药研发的重要宝库,在我国有悠久的药用历史,是历代医家临床经验的总结。为支持经典名方开发,国家及相关管理部门先后发布了相关鼓励性政策。处方药味炮制方法的考证及确定是经典名方开发过程中的关键问题之一,目前还未能形成统一的共识和标准。该文对经典名方中的药味炮制相关内容进行梳理分析,总结了《古代经典名方目录(第一批)》中炮制方法的特点和考证面临的问题,提出了炮制考证方法建议,即梳理经典名方所处时期药味对应的主流方法,厘清炮制方法历代变迁情况,根据医家炮制用药特色确定炮制方法,根据炮制作用确定炮制方法并结合临床功效及适应症辨别炮制方法4个研究策略,以期为经典名方中涉及的炮制研究提供思路和参考。

As an important treasure for the research and development of new Chinese medicines,the classical prescriptions have a long medical history in China and are the summary of the clinical experience of the medical experts in the past dynasties.To support the research and development of classical prescriptions,relevant encouraging policies were issued by the state and relevant administrative departments.It is one of the key problems in the development process of classical prescriptions to verify and determine the processing methods of prescription herbal drugs.At present,there is no consensus or standard on such problems of classical prescriptions.In this paper,we sorted out and analyzed the related content of the herb processing for classical prescriptions,summarized the characteristics of the processing methods in the Catalogue of classical prescriptions(First Batch)and the problems faced in the textual research,and put forward some suggestions on the processing and textual research,including four research strategies:sorting out the mainstream methods for herbs in various periods of classical prescriptions,clarifying histological changes in the processing methods,determining the processing methods based on the drug processing characteristics,determining the processing methods based on the processing functions and identifying the processing methods according to the clinical efficacy and indication,so as to provide ideas and references for the research of processing methods involved in classical prescriptions.