Time to relapse after treatment withdrawal for different biologics used to treat plaque psoriasis

Psoriasis is a common chronic recurrent inflammatory disease.Plaque psoriasis accounts for more than 90%of psoriasis patients.Currently,no therapies are curative.Biologics have greatly improved the clinical efficacy and potentially provide a better long-term safety profile,with respect to toxicity to major organs,than conventional treatments;however,relapse after treatment withdrawal is still an important issue.Although maintenance treatment is recommended in most guidelines,treatment withdrawal occurs quite frequently in real-world clinical practice.Thus,the time to relapse is an important consideration when choosing among the different therapies.