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二肽基肽酶4抑制剂/二甲双胍固定剂量复方制剂的临床应用专家建议

Experts recommendation for dipeptidyl peptidaseⅣinhibitors/metformin fixed-dose combination therapies in patients with type 2 diabetes mellitus
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摘要 二肽基肽酶4(DPP-4)抑制剂和二甲双胍联合应用,针对2型糖尿病不同的病理生理缺陷发挥机制互补、协同增效的降糖作用。DPP-4抑制剂/二甲双胍固定剂量复方制剂(FDC)和等剂量DPP-4抑制剂、二甲双胍自由联合相比,具有良好的生物等效性。与两种药物自由联合相比,FDC可简化治疗方案,提高患者治疗依从性。笔者重点围绕DPP-4抑制剂/二甲双胍FDC的有效性和安全性、优势和局限性、适用人群以及使用注意事项等提出建议。
作者 中华医学会内分泌学分会神经与内分泌学组 母义明 朱大龙 赵家军 余学锋 谷伟军 Neuroendocrine Expert Panel,Chinese Society of Endocrinology;Mu Yiming;Zhu Dalong;Zhao Jiajun(不详;Department of Endocrinlolgy,the First Medical Center of PLA General Hospital,Beijing 100853,China;Department of Endocrinology,Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University,Nanjing 210008,China;Department of Endocrinology,Shandong Provincial Hospital,Jinan 250021,China)
机构地区 不详 解放军总医院第一医学中心内分泌科 南京大学医学院附属鼓楼医院内分泌科 山东省立医院内分泌科 华中科技大学同济医学院附属同济医院内分泌科
出处 《中华糖尿病杂志》 CAS CSCD 北大核心 2020年第12期949-953,共5页 CHINESE JOURNAL OF DIABETES MELLITUS
关键词 糖尿病 2型 二肽基肽酶4抑制剂 二甲双胍 固定剂量复方制剂
分类号 R977.15 [医药卫生—药品]
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中华糖尿病杂志
2020年 第12期

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