宫颈癌术后淋巴囊肿形成及感染的影响因素

Factors influencing lymphocele formation and infection after cervical cancer surgery

目的分析宫颈癌术后淋巴囊肿形成及感染的影响因素。方法回顾性分析宫颈癌患者258例的临床资料,分析宫颈癌术后淋巴囊肿形成及感染的影响因素。结果258例患者中,81例宫颈癌术后形成淋巴囊肿。多因素logistic回归分析显示,临床分期Ⅱ期、切除淋巴结数目>20枚、术后24-h引流量>100 mL、术后放化疗和术后血清白蛋白<35 g/L是宫颈癌术后淋巴囊肿形成的危险因素(P<0.05)。81例淋巴囊肿患者中,11例发生了感染。多因素logistic回归分析显示,合并糖尿病、术后放化疗和淋巴囊肿直径>5 cm是淋巴囊肿感染的危险因素(P<0.05)。结论临床分期Ⅱ期、切除淋巴结数目>20枚、术后24-h引流量>100 mL、术后放化疗和术后血清白蛋白<35 g/L是宫颈癌术后容易形成淋巴囊肿的重要因素,合并糖尿病、术后放化疗和淋巴囊肿直径>5 cm者更容易发生宫颈癌术后淋巴囊肿感染。

Objective To analyze the factors influencing lymphocele formation and infection after cervical cancer surgery.Methods The clinical data of 258 patients underwent cervical cancer were retrospectively analyzed.The factors for lymphocele formation and infection after cervical cancer surgery were analyzed.Results Of 258 cases,lymphocele occurred in 81 cases.Multivariate logistic regression analysis showed that the clinical stageⅡ,more than 20 lymph nodes resected,24-h drainage volume more than 100 mL after operation,postoperative serum albumin<35 g/L,and combined use of radiation and chemotherapy after operation were the risk factors for lymphocele formation after cervical cancer surgery(P<0.05).Of 81 patients with lymphocele,11 cases developed infection.Multivariate logistic regression analysis showed that the patients complicated with diabetes,having lymphocele diameter>5 cm and combined use of radiation and chemotherapy after operation were the risk factors for lymphocele infection(P<0.05).Conclusion The clinical stageⅡ,more than 20 lymph nodes resected,24-h drainage volume more than 100 mL after operation,postoperative serum albumin less than 35 g/L,combined use of radiation and chemotherapy after operation are the important factors for lymphocele formation after cervical cancer surgery.The patients complicated with diabetes and with lymphocele diameter>5 cm,and combined use of radiation and chemotherapy after operation are more likely to have lymphocele infection after cervical cancer surgery.