摘要
人类Pegivirus病毒主要经非消化道途径传播,在人群中普遍存在。该病毒对人类的致病性不强,单独感染对健康人群、肝炎患者以及器官移植患者预后均无明显影响。但是该病毒感染后可降低获得性免疫缺陷综合征和埃博拉出血热等传染病的死亡率,由此被认为是一种潜在的“保护性病毒”。同时,该病毒也是某些疾病(如非霍奇金淋巴瘤、肝炎相关性再生障碍性贫血等)的危险因素。对于该病毒在不同疾病中表现出的致病性,目前尚缺乏深入的系统研究。
The human Pegivirus is mainly transmitted through non-digestive tract and is common in the general population.The virus has no strong pathogenicity to human,and its single infection has no significant impact on healthy people,hepatitis patients and the prognosis of organ transplant patients.But Pegivirus infection can reduce the mortality of infectious disease such as acquired immunodeficiency syndrome and Ebola hemorrhagic fever,and it is considered as a potential"protective virus".Meanwhile,the virus might also be a risk factor for some diseases such as non-Hodgkin′s lymphoma,hepatitis-related aplastic anemia,etc.As for its viral pathogenicity in different diseases,currently there are no systematic research.
作者
李占甲
陈水平
LI Zhanjia;CHEN Shuiping(PLA 307 Medical College of Anhui Medical University,Beijing 100071,China;Department of Laboratory Medicine,the Fifth Medical Center of Chinese PLA General Hospital,Beijing 100071,China;Department of Infection Control,the Fifth Medical Center of Chinese PLA General Hospital,Beijing 100071,China)
出处
《医学综述》
2021年第1期24-28,35,共6页
Medical Recapitulate
基金
解放军总医院军事医学青年项目成长专项课题(QNC19035)。
