干眼症的临床治疗进展

Progress in the clinical treatment of xerophthalmia

干眼症是眼科临床最为常见的眼表疾病之一,药物治疗是干眼症最主要的治疗手段。人工泪液类滴眼液是任何类型干眼症的基础治疗药物,为临床一线药物。非甾体抗炎药和皮质类固醇作为干眼症的辅助用药,能有效缓解干眼症的临床症状。免疫抑制剂可作为重度干眼的长期用药。自体血清、地夸磷索四钠和中医药等逐步应用于眼科临床。角膜接触镜、湿房镜、泪点栓塞等新型治疗方式不断丰富,且有广阔的发展前景。

Xerophthalmia(dry eye)is one of the most common ocular surface diseases in ophthalmology.Drug therapy is the main treatment for xerophthalmia.Artificial tears eye drops are the basic therapeutic drugs for any xerophthalmia and are the first-line clinical drugs.Non-steroidal anti-inflammatory drugs(NSAIDs)and corticosteroids can effectively relieve the symptoms of xerophthalmia.Immunosuppressants can be used for long-term treatment of severe xerophthalmia.Autogenous serum,diquafosol tetrasodium,and traditional Chinese medicine have been gradually used in clinical ophthalmology.Contact lens,wet chamber lens,lacrimal embolism,and other new treatment methods are continuously enriched and have broad prospects for development.