临床药师参与治疗一例病态肥胖患者丹毒感染的病例分析

Participation of clinical pharmacists in one case of erysipelas infection in a morbidly obese patient

目的探讨临床药师在1例病态肥胖丹毒患者抗感染治疗中发挥的作用。方法临床药师参与1例病态肥胖丹毒患者抗感染治疗方案的调整,根据该病态肥胖患者体内药代动力学变化,结合国内外相关文献,建议该患者抗感染药物的剂量分别为:青霉素480万IU ivd q6h、头孢曲松4g ivd qd、左氧氟沙星750mg ivd qd,以此给予医师以参考。结果临床药师后续的建议被医师所采纳,临床药师协助医师制订个体化给药方案,患者丹毒感染得到了有效控制。结论临床药师找好药学服务切入点,发挥自身专业优势,与医师、护师组成医疗团队,更好地为患者服务。同时该病例也为病态肥胖患者抗感染药物剂量调整提供了参考。

Objective To explore the role of clinical pharmacists in anti-infection treatment of morbidly obese patients with erysipelas. Methods Clinical pharmacists participated in the adjustment of anti-infection treatment drugs for the morbidly obese patient. According to the pharmacokinetic changes of the morbidly obese patient, combined with domestic and foreign literatures, it was suggested that the doses of anti-infective drugs for this patient were respectively: penicillin 4800000 IU ivd q6h, ceftriaxone 4g ivd qd, and levofloxacin 750 mg ivd qd, which could be given to physicians as a reference. Results The follow-up advice of clinical pharmacists was adopted by physicians. Ultimately, clinical pharmacists assisted physicians to develop individual treatment programs, and the erysipelas infection was effectively controlled. Conclusion Clinical pharmacists should participate in the medical team of physicians and nurses to deliver better services to patients by finding key points to carry out pharmaceutical care and taking advantages of professional knowledge. What is more, this case also provided a reference for morbidly obese patients to adjust the dose of anti-infection drugs.