补肾调经汤治疗多囊卵巢综合征不孕疗效及其对性激素水平的影响

Analysis on the Effect of Bushen Tiaojing Decoction on Infertility of Polycystic Ovary Syndrome and Its Influence on the Level of Sex Hormones

目的探析肾虚型多囊卵巢综合征所致不孕患者采用补肾调经汤治疗的应用价值。方法将2018年8月—2019年8月收治的100例多囊卵巢综合征肾虚型所致不孕的患者作为研究对象。采用计算机软件将其随机分为研究组与对照组,分别采取滋肾育胎丸+补肾调经汤联合治疗和滋肾育胎丸单独治疗。对2组妊娠率、排卵率、中医证候积分、子宫内膜厚度、卵巢体积、性激素水平进行对比。结果研究组患者的妊娠率为76.00%、排卵率为90.00%,对照组患者的妊娠率为40.00%、排卵率为62.00%,研究组患者的妊娠率、排卵率均高于对照组,差异明显(P<0.05)。在中医证候积分、子宫内膜厚度、卵巢体积、LH、FSH和T方面,治疗前,研究组与对照组差异无统计学意义(P>0.05);治疗后,研究组均比对照组优,差异有统计学意义(P<0.05)。结论多囊卵巢综合征肾虚型所致不孕的患者采用补肾调经汤进行治疗,可显著提高患者的排卵率与妊娠率,有效改善患者的中医证候积分、卵巢体积、子宫内膜厚度和性激素水平,该治疗方式的临床应用价值显著,值得进一步在临床推广使用。

Objective To explore the application value of Bushen Tiaojing decoction in the treatment of infertility caused by polycystic ovary syndrome(PCOS).Methods From August 2018 to August 2019,100 patients with infertility caused by kidney deficiency syndrome PCOS were studied.It was randomly divided into study group and control group by computer software,and were treated with Zishen Yutai pill combined with Bushen Tiaojing decoction and Zishen Yutai pill separately.The pregnancy rate,ovulation rate,TCM syndrome score,endometrial thickness,ovarian volume and sex hormone level were compared between the two groups.Results The pregnancy rate and ovulation rate were 76.00%and 90.00%in the study group,40.00%and 62.00%in the control group.The pregnancy rate and ovulation rate of the patients in the study group were higher than those in the control group,and there had significant difference(P<0.05).In TCM symptom score,endometrial thickness,ovarian volume,LH,FSH and T,before treatment,there was little difference between the study group and the control group(P>0.05).After treatment,the study group was better than the control group,and there had significant difference(P<0.05).Conclusion Bushen Tiaojing decoction can significantly improve the ovulation rate and pregnancy rate,and effectively improve the TCM syndrome score,ovarian volume,endometrial thickness and sex hormone level of patients with infertility caused by kidney deficiency syndrome PCOS.The clinical application value of this treatment is significant,which is worthy of further promotion in clinical use.