摘要
目的探讨腰椎间盘突出症患者采用加味身痛逐瘀汤配合针刺治疗,对患者腰椎功能及炎症因子IL-2、IL-10水平的影响。方法回顾性分析2017年2月—2019年3月160例腰椎间盘突出症患者临床资料,根据治疗方式不同分为对照组(80例)和观察组(80例)。对照组给予单纯针刺治疗,观察组在对照组基础上联合给予加味身痛逐瘀汤口服治疗。比较2组治疗2个疗程后总有效率、治疗前与治疗2个疗程后JOA腰椎功能、炎症因子血清IL-2、IL-10、TNF-α水平和治疗结束6个月后2组复发率。结果治疗2个疗程后,观察组总有效率为90.00%,大于对照组60.00%(P<0.05);与治疗前相比,治疗2个疗程后2组的JOA评分显著下降,且观察组低于对照组(P<0.05);与治疗前相比,治疗2个疗程后2组血清IL-2、TNF-α均下降,观察组低于对照组;2组血清IL-10明显升高,且观察组高于对照组(P<0.05);治疗结束6个月后,观察组复发率为4.35%,低于对照组复发率27.27%(P<0.05)。结论腰椎间突出症患者采用加味身痛逐瘀汤联合针刺治疗,显著改善患者腰椎功能,降低炎症因子水平,减少复发率,提高安全性,值得推广。
Objective To discuss the effect of modified Shentong Zhuyu decoction combined with acupuncture treatment on lumbar vertebrae function and inflammatory factor IL-2 and IL-10 level in patients with lumbar disc herniation.Methods Retrospective analysis of the clinical data of 160 patients with lumbar disc herniation from February 2017 to March 2019 was carried out.They ere divided into control group(n=80)and observation group(n=80)according to different treatment methods.The control group was treated with acupuncture alone.On the basis of the control group,the observation group was given oral treatment of modified Shentong Zhuyu decoction.The total effective rate after 2 courses of treatment,the lumbar function,the level of inflammatory factor serum IL-2,IL-10,TNF-αand the recurrence rate JOA the two groups after 6 months of treatment before and after treatment was compared.Results After two courses of treatment,the total effective rate of observation group was 90.00%,which was higher than that of control group(60.00%)(P<0.05).The JOA scores of the two groups decreased significantly after 2 courses of treatment compared with before treatment,and the observation group was lower than that of the control group(P<0.05).The serum IL-2 TNF-αof the two groups decreased after 2 courses of treatment compared with before treatment,the observation group was lower than the control group,the serum IL-10 of the two groups was significantly higher,and the observation group was higher than the control group(P<0.05).After 6 months of treatment,the recurrence rate in the observation group was 4.35%,which was lower than that in the control group(27.27%)(P<0.05).Conclusion Modified Shentong Zhuyu decoction combined with acupuncture significantly improved the lumbar function of patients,reduced the level of inflammatory factors,reduced the recurrence rate,and improved the safety,which is worth popularizing.
作者
李世强
LI Shiqiang(Department of Traditional Chinese Medicine Soft Injury Rehabilitation,Shenyang 739 Hospital,Liaoning Province,Shenyang 110034,China)
出处
《光明中医》
2020年第24期3852-3855,共4页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
痹证
腰椎间盘突出症
针刺疗法
身痛逐瘀汤
腰椎功能
中医综合疗法
arthromyodynia
lumbar disc herniation
acupuncture therapy
modified Shentong Zhuyu decoction
lumbar function
interleukin 2
interleukin 10
influence
comprehensive therapy of TCM