心力衰竭与糖尿病共病及其临床用药研究现状

Status quo of research on comorbidity of heart failure and diabetes and its clinical medication

心力衰竭和糖尿病是现代两种重大的流行病,二者之间交互影响。临床常见心力衰竭与糖尿病共病,对临床用药安全提出了新的挑战。本文从流行病学、临床症状及预后风险、生理病理机制及用药选择4个方面对“心力衰竭与糖尿病共病”的研究现状进行系统阐述,并重点论证将心力衰竭和糖尿病单病药物应用于共病患者的安全性及有效性,为临床用药决策提供指导。

Heart failure and diabetes are two most frequent conditions in the modern times that interact with each other.Comorbidity of heart failure and diabetes is clinically common,posing new challenges to the safety of clinical medication.This paper provides a systematical review of the status quo of research on the comorbidity in the aspects of epidemiology,clinical symptoms and risk of prognosis,physiological and pathological mechanism,and drug selection,focusing on the safety and effectiveness of using drugs for heart failure and diabetes for patients with the comorbidity,to provide guidance for decision making in clinical medication.