流程质控在急性缺血性卒中静脉溶栓治疗中的应用

Application of quality process control in intravenous thrombolytic therapy for acute ischemic stroke

目的:探讨静脉溶栓流程质控对急性缺血性卒中患者的应用效果。方法:急性缺血性卒中188例患者进行静脉溶栓治疗,其中流程质控115例(观察组),常规进行静脉溶栓治疗73例(对照组)。通过比较两组患者到达医院至使用溶栓药物的时间(door to needle time,DNT)及溶栓前后美国国立卫生研究院卒中量表(National Institutes of Health stroke scale,NIHSS)评分,评估流程质控的疗效。结果:观察组DNT和各个时间节点所需时间较对照组明显缩短(P<0.05)。治疗后观察组患者NIHSS评分较对照组明显改善(P<0.05)。结论:流程质控可明显缩短急性缺血性卒中患者DNT,改善NIHSS评分,溶栓效率明显提高,进一步使患者获益。

Objective:To investigate the effect of process quality control of intravenous thrombolysis therapy on patients with acute ischemic stroke.Methods:188 patients with acute ischemic stroke were treated with intravenous thrombolytic therapy,115 of whom were treated with process quality control and set as observation group.Another 73 patients were treated with intravenous thrombolysis as control group.The time from arrival in hospital to intravenous thrombolytic therapy(door to needle time,DNT)and National Institutes of Health stroke scale(NIHSS)score before and after thrombolytic therapy were used in the two groups to evaluate the efficacy of process quality control.Results:The DNT and time nodes in the observation group were significantly shorter than those in the control group(P<0.05).After treatment,the NIHSS score of the observation group was significantly improved compared with the control group(P<0.05).Conclusion:Process quality control can significantly shorten DNT in patients with acute ischemic stroke,improve NIHSS score,significantly improve thrombolysis efficiency,and further benefit the patients.