颅底脊索瘤的研究进展

Research progress of skull base chordoma

颅底脊索瘤(SBC)是一种局部侵袭性肿瘤,可沿颅底侵犯并向不同方向扩展。尽管它们在组织学上是低度恶性的,但易侵及周围血管神经,使得在大多数情况下几乎不可能完全切除,这导致手术后残留肿瘤。目前对其治疗主要是手术及放射治疗,但复发率高,预后差。该文就颅底脊索瘤最新研究进展做一综述,以便对颅底脊索瘤的治疗提供帮助。

Skull base chordoma is a locally invasive tumor,which can expand in different directions with the invasion of skull base.Although they are histologically low-grade,they easily invade peripheral blood vessels and nerves,which makes it almost impossible to completely remove them in most cases,which leads to residual tumors after surgery.At present,the main treatments are surgery and radiotherapy,but the recurrence rate is high and the prognosis is poor.This article reviews the latest research progress of skull base chordoma,so as to provide help for the treatment of skull base chordoma.