左心耳封堵术对患者系统内稳态的影响

Effect of Left Atrial Appendage Closure on Systemic Homeostasis in Patients

目前世界范围内非瓣膜性心房颤动患者人数逐年增加,这种疾病的远期危害较大,其导致的脑卒中及体循环栓塞事件常可危及生命,并严重影响患者的生存质量。预防心房颤动相关脑卒中已成为心房颤动患者综合管理策略中的主要内容。作为预防非瓣膜性心房颤动相关脑卒中的新技术,左心耳封堵术的疗效和安全性越来越得到证实,但有关左心耳封堵术对患者系统内稳态影响的临床研究较少。现对此做系统综述,探讨左心耳封堵术对系统内稳态的影响。

At present,the number of patients with nonvalvular atrial fibrillation is increasing year by year in the world,and the long-term harm of this disease is great.Stroke and systemic circulation embolism events caused by nonvalvular atrial fibrillation can often endanger life and seriously affect the quality of life of patients.The prevention of stroke related to atrial fibrillation has become the main content of comprehensive management strategies for patients with atrial fibrillation.As a new technique for the prevention of stroke in nonvalvular atrial fibrillation,the efficacy and safety of left atrial appendage closure have been increasingly confirmed.However,there are few clinical studies on the effect of left atrial appendage closure on patients systemic homeostasis.This paper makes a systematic review to explore the influence of left atrial appendage closure on the systemic homeostasis.